Thanks for your response. To clarify, this is more about the files & less about the applications. These departments absolutely rely every day on the applications that come as a part of Adobe CC. Other departments do not. The departments using primarily Macs will frequently be pointed at SharePoint libraries that other departments have shared with them; they also have their own site collections & libraries available to them within our organization. Everyone in our environment has access to OneDrive & SharePoint libraries.
As a temporary workaround, for the last six months or so, we have had a server set up with the OneDrive client that then shares the synced libraries as a single SMB share so that they can connect & function normally while not filling up each of their own Mac’s hard drives with an exact replica of mostly irrelevant files. While this does work, there are some limitations, but for now it has been the closest to ideal that we can come.
For the moment we’re just brainstorming, but I do appreciate your taking the time to respond.